U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

catp-2 Cation-transporting P-type ATPase N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 182114, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
catp-2
Official Full Name
Cation-transporting P-type ATPase N-terminal domain-containing protein
Primary source
WormBase:WBGene00015338
Locus tag
CELE_C02E7.1
See related
AllianceGenome:WB:WBGene00015338
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable P-type sodium:potassium-exchanging transporter activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit) and ATP4A (ATPase H+/K+ transporting subunit alpha). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See catp-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (4934706..4939085)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Seven TM Receptor Neighboring gene LITAF domain-containing protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Na+/K+ ATPase regulates the expression and localization of acetylcholine receptors in a pump activity-independent manner. Doi M, et al. Mol Cell Neurosci, 2008 Aug. PMID 18599311, Free PMC Article
  2. The Na(+)-K(+)-ATPase is needed in glia of touch receptors for responses to touch in C. elegans. Johnson CK, et al. J Neurophysiol, 2020 May 1. PMID 32292107, Free PMC Article
  3. Exon-dependent transcriptional adaptation by exon-junction complex proteins Y14/RNP-4 and MAGOH/MAG-1 in Caenorhabditis elegans. Fernandez-Abascal J, et al. PLoS Genet, 2022 Oct. PMID 36315586, Free PMC Article
  4. The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans. Jofré DM, et al. Proc Natl Acad Sci U S A, 2022 Apr 12. PMID 35394881, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables P-type sodium:potassium-exchanging transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in establishment or maintenance of transmembrane electrochemical gradient IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular potassium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular sodium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion export across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Cation-transporting P-type ATPase N-terminal domain-containing protein
NP_001309616.1
  • Partially confirmed by transcript evidence
NP_504328.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    4934706..4939085
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071927.2 → NP_504328.1  Cation-transporting P-type ATPase N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504328.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16436
    Conserved Domains (1) summary
    cl21460
    Location:66 → 1040
    HAD_like; Haloacid Dehalogenase-like Hydrolases

  2. NM_001322555.1 → NP_001309616.1  Cation-transporting P-type ATPase N-terminal domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MBN3
    Conserved Domains (1) summary
    cl21460
    Location:61 → 1035
    HAD_like; Haloacid Dehalogenase-like Hydrolases
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools