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nhr-149 NR LBD domain-containing protein;Nuclear Hormone Receptor family [ Caenorhabditis elegans ]

Gene ID: 182174, updated on 2-Nov-2024

Summary

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Official Symbol
nhr-149
Official Full Name
NR LBD domain-containing protein;Nuclear Hormone Receptor family
Primary source
WormBase:WBGene00015397
Locus tag
CELE_C03G6.12
See related
AllianceGenome:WB:WBGene00015397
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nhr-149 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (7348211..7349641, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Nuclear Hormone Receptor family Neighboring gene Nuclear Hormone Receptor family Neighboring gene Serpentine Receptor, class H Neighboring gene Nuclear Hormone Receptor family Neighboring gene Serpentine Receptor, class H Neighboring gene Serpentine Receptor, class H

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NR LBD domain-containing protein;Nuclear Hormone Receptor family
NP_001309617.1
  • Confirmed by transcript evidence
NP_504874.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    7348211..7349641 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072473.5 → NP_504874.2  Nuclear Hormone Receptor family [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MB42
    Conserved Domains (2) summary
    smart00399
    Location:6 → 78
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
    smart00430
    Location:190 → 342
    HOLI; Ligand binding domain of hormone receptors

  2. NM_001322569.3 → NP_001309617.1  NR LBD domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MB07
    Conserved Domains (2) summary
    smart00430
    Location:133 → 285
    HOLI; Ligand binding domain of hormone receptors
    cl02596
    Location:5 → 25
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
Nucleotide Protein
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Gene LinkOut

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