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glb-3 GLOBIN domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 182348, updated on 2-Nov-2024

Summary

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Official Symbol
glb-3
Official Full Name
GLOBIN domain-containing protein
Primary source
WormBase:WBGene00007389
Locus tag
CELE_C06H2.5
See related
AllianceGenome:WB:WBGene00007389
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Is expressed in neurons; non-striated muscle; and somatic nervous system. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See glb-3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (11134596..11140814)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Glucosamine 6-phosphate N-acetyltransferase;N-acetyltransferase domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Folate transporter 1 Neighboring gene F-box domain-containing protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. GLB-3: A resilient, cysteine-rich, membrane-tethered globin expressed in the reproductive and nervous system of Caenorhabditis elegans. Hafideddine Z, et al. J Inorg Biochem, 2023 Jan. PMID 36370505
  2. Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. Hoogewijs D, et al. BMC Genomics, 2007 Oct 4. PMID 17916248, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables oxygen binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxygen binding IEA
Inferred from Electronic Annotation
more info
  
enables oxygen carrier activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in oxygen transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to hypoxia IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
GLOBIN domain-containing protein
NP_001367199.1
  • Confirmed by transcript evidence
NP_001367200.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    11134596..11140814
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001380758.2 → NP_001367199.1  GLOBIN domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    B6EU61
    Conserved Domains (1) summary
    cd01040
    Location:42 → 177
    Mb-like; myoglobin-like; M family globin domain

  2. NM_001380757.1 → NP_001367200.1  GLOBIN domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    B6EU62
    Conserved Domains (1) summary
    cd01040
    Location:114 → 249
    Mb-like; myoglobin-like; M family globin domain
Nucleotide Protein
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