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hdl-2 Histidine Decarboxyase Like [ Caenorhabditis elegans ]

Gene ID: 182464, updated on 2-Nov-2024

Summary

Official Symbol
hdl-2
Official Full Name
Histidine Decarboxyase Like
Primary source
WormBase:WBGene00006409
Locus tag
CELE_C09G9.4
See related
AllianceGenome:WB:WBGene00006409
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable carboxy-lyase activity. Predicted to be involved in amino acid metabolic process and carboxylic acid metabolic process. Predicted to be located in membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See hdl-2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
13
Sequence:
Chromosome: IV; NC_003282.8 (8874147..8877022)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene C6 domain-containing protein Neighboring gene pseudo Neighboring gene Paired domain-containing protein Neighboring gene ncRNA Neighboring gene FIP (Fungus-Induced Protein) Related;TransThyretin-Related family domain

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carbon-carbon lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables carboxy-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables carboxy-lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in carboxylic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Histidine Decarboxyase Like
NP_501539.3
  • Product from WormBase gene class hdl;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    8874147..8877022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069138.5NP_501539.3  Histidine Decarboxyase Like [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501539.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17874
    Conserved Domains (1) summary
    cl18945
    Location:125527
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...