U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cal-2 EF-hand domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 182789, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
cal-2
Official Full Name
EF-hand domain-containing protein
Primary source
WormBase:WBGene00000286
Locus tag
CELE_C18E9.1
See related
AllianceGenome:WB:WBGene00000286
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable calcium ion binding activity. Predicted to be active in centrosome and cytoplasm. Is expressed in head neurons; hypodermis; and tail neurons. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See cal-2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (8960714..8961569)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Vesicle transport protein Neighboring gene ncRNA Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 Neighboring gene Translocation protein SEC62

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Transgenic reporter analysis of ChIP-Seq-defined enhancers identifies novel target genes for the terminal selector UNC-3/Collier/Ebf. Li Y, et al. MicroPubl Biol, 2021. PMID 34549172, Free PMC Article
  2. Cytokinesis is not controlled by calmodulin or myosin light chain kinase in the Caenorhabditis elegans early embryo. Batchelder EL, et al. FEBS Lett, 2007 Sep 4. PMID 17716666, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
EF-hand domain-containing protein
NP_495906.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8960714..8961569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063505.6 → NP_495906.2  EF-hand domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495906.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EEG0
    Conserved Domains (2) summary
    PTZ00184
    Location:27 → 165
    PTZ00184; calmodulin; Provisional
    cd00051
    Location:108 → 166
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools