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xbx-4 DUF3719 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 182822, updated on 2-Nov-2024

Summary

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Official Symbol
xbx-4
Official Full Name
DUF3719 domain-containing protein
Primary source
WormBase:WBGene00016025
Locus tag
CELE_C23H5.3
See related
AllianceGenome:WB:WBGene00016025
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Is expressed in ciliated neurons; head neurons; and sensory neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See xbx-4 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (2114637..2115829)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Cyclic nucleotide-binding domain-containing protein Neighboring gene BURP domain-containing protein;Reelin domain-containing protein;Uncharacterized protein Neighboring gene ncRNA Neighboring gene Globin domain-containing protein Neighboring gene Ground-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. xbx-4, a homolog of the Joubert syndrome gene FAM149B1, acts via the CCRK and RCK kinase cascade to regulate cilia morphology. Maurya AK, et al. Curr Biol, 2021 Dec 20. PMID 34731674, Free PMC Article
  2. Analysis of xbx genes in C. elegans. Efimenko E, et al. Development, 2005 Apr. PMID 15790967
  3. The C. elegans regulatory factor X (RFX) DAF-19M module: A shift from general ciliogenesis to cell-specific ciliary and behavioral specialization. Ahn S, et al. Cell Rep, 2022 Apr 12. PMID 35417689
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. xbx-4, a homolog of the Joubert syndrome gene FAM149B1, acts via the CCRK and RCK kinase cascade to regulate cilia morphology.
    Title: xbx-4, a homolog of the Joubert syndrome gene FAM149B1, acts via the CCRK and RCK kinase cascade to regulate cilia morphology.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

General protein information

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Preferred Names
DUF3719 domain-containing protein
NP_500165.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    2114637..2115829
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067764.5 → NP_500165.1  DUF3719 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500165.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O61830
    Conserved Domains (1) summary
    pfam12516
    Location:36 → 76
    DUF3719; Protein of unknown function (DUF3719)
Nucleotide Protein
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