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let-391 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 182953, updated on 2-Nov-2024

Summary

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Official Symbol
let-391
Official Full Name
C2H2-type domain-containing protein
Primary source
WormBase:WBGene00006492
Locus tag
CELE_C27A12.3
See related
AllianceGenome:WB:WBGene00006492
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See let-391 in Genome Data Viewer
Location:
chromosome: I
Exon count:
8
Sequence:
Chromosome: I; NC_003279.8 (6038403..6041267)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol 3-kinase catalytic subunit type 3 Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA Neighboring gene Homeobox protein ceh-2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alignment of the genetic and physical maps in the dpy-5 bli-4 (I) region of C. elegans by the serial cosmid rescue of lethal mutations. McDowall JS, et al. Mol Gen Genet, 1997 Jun. PMID 9230901
  2. Genetic analysis of sterile mutants in the dpy-5 unc-13 (I) genomic region of Caenorhabditis elegans. McDowall JS, et al. Mol Gen Genet, 1997 Jun. PMID 9230900
  3. Allelic ratios and the mutational landscape reveal biologically significant heterozygous SNVs. Chu JS, et al. Genetics, 2012 Apr. PMID 22267497, Free PMC Article
  4. Mutational accessibility of essential genes on chromosome I(left) in Caenorhabditis elegans. Johnsen RC, et al. Mol Gen Genet, 2000 Mar. PMID 10778742
  5. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
C2H2-type domain-containing protein
NP_491744.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6038403..6041267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059343.8 → NP_491744.3  C2H2-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491744.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01960
    Conserved Domains (2) summary
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:73 → 96
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
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