odd-2 Protein odd-skipped-related 2 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: odd-2
Official Full Name: Protein odd-skipped-related 2
Primary source: WormBase:WBGene00003846
Locus tag: CELE_C34H3.2
See related: AllianceGenome:WB:WBGene00003846
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and pattern specification process. Predicted to be active in nucleus. Is expressed in intestine and tail. Orthologous to human OSR2 (odd-skipped related transciption factor 2) and OSR1 (odd-skipped related transcription factor 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See odd-2 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 2

Sequence:: Chromosome: X; NC_003284.9 (6159377..6160527, complement)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

role in gut specification
Title: odd-skipped homologs function during gut development in C. elegans.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C34H3.a (e-PCR)
- UniSTS:322499

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in animal organ morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in pattern specification process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Protein odd-skipped-related 2

NP_509032.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

6159377..6160527 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_076631.5 → NP_509032.1 Protein odd-skipped-related 2 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_509032.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9N5X6

Conserved Domains (3) summary

sd00017
Location:126 → 146

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:124 → 146

zf-C2H2; Zinc finger, C2H2 type

pfam13465
Location:138 → 163

zf-H2C2_2; Zinc-finger double domain