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cyp-25A4 Cytochrome P450 [ Caenorhabditis elegans ]

Gene ID: 183248, updated on 2-Nov-2024

Summary

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Official Symbol
cyp-25A4
Official Full Name
Cytochrome P450
Primary source
WormBase:WBGene00007967
Locus tag
CELE_C36A4.6
See related
AllianceGenome:WB:WBGene00007967
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cyp-25A4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (3849745..3852080, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene putative UDP-N-acetylglucosamine pyrophosphorylase Neighboring gene Microtubule-associated protein futsch Neighboring gene ncRNA Neighboring gene Breast cancer type 1 susceptibility protein homolog;RING-type E3 ubiquitin transferase BRCA1 Neighboring gene pseudo Neighboring gene Acetyl-coenzyme A synthetase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Aryl Hydrocarbon Receptor-Dependent and -Independent Pathways Mediate Curcumin Anti-Aging Effects. Brinkmann V, et al. Antioxidants (Basel), 2022 Mar 23. PMID 35453298, Free PMC Article
  2. Cytochrome P450s and short-chain dehydrogenases mediate the toxicogenomic response of PCB52 in the nematode Caenorhabditis elegans. Menzel R, et al. J Mol Biol, 2007 Jun 29. PMID 17499272
  3. Increasing Complexity of the N-Glycome During Caenorhabditis Development. Wilson IBH, et al. Mol Cell Proteomics, 2023 Mar. PMID 36717059, Free PMC Article
  4. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cytochrome P450
NP_497779.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    3849745..3852080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065378.3 → NP_497779.1  Cytochrome P450 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497779.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q27479
    Conserved Domains (1) summary
    pfam00067
    Location:37 → 489
    p450; Cytochrome P450
Nucleotide Protein
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