U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

C42C1.19 MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 183402, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
C42C1.19
Official Full Name
MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein
Primary source
WormBase:WBGene00302978
Locus tag
CELE_C42C1.19
See related
AllianceGenome:WB:WBGene00302978
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glucose 6-phosphate:phosphate antiporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II; glycogen storage disease Ib; and glycogen storage disease Ic. Orthologous to human SLC37A4 (solute carrier family 37 member 4). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See C42C1.19 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (12282739..12287838)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Protein-lysine methyltransferase C42C1.13 Neighboring gene Aminopeptidase ltah-1.1 Neighboring gene PAP2_C domain-containing protein Neighboring gene Mitochondrial thiamine pyrophosphate carrier Neighboring gene Erlin Neighboring gene Protein kinase domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables glucose 6-phosphate:phosphate antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glucose-6-phosphate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphate ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein
NP_001255630.1
  • Confirmed by transcript evidence
NP_001255633.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12282739..12287838
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268701.2 → NP_001255630.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255630.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C0RSI9
    Conserved Domains (1) summary
    cd17312
    Location:7 → 389
    MFS_OPA_SLC37; Organophosphate:Pi antiporter/Solute Carrier family 37 of the Major Facilitator Superfamily of transporters

  2. NM_001268704.3 → NP_001255633.1  MFS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255633.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A3QMC7
    Conserved Domains (1) summary
    cl28910
    Location:1 → 286
    MFS; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous