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npr-18 Neuropeptide receptor 18 [ Caenorhabditis elegans ]

Gene ID: 183408, updated on 2-Nov-2024

Summary

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Official Symbol
npr-18
Official Full Name
Neuropeptide receptor 18
Primary source
WormBase:WBGene00008065
Locus tag
CELE_C43C3.2
See related
AllianceGenome:WB:WBGene00008065
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Is expressed in neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See npr-18 in Genome Data Viewer
Location:
chromosome: X
Exon count:
12
Sequence:
Chromosome: X; NC_003284.9 (9690745..9696723)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Penicillin-binding protein Neighboring gene Intermediate filament protein ifp-1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein dyf-7 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dissecting the signaling mechanisms underlying recognition and preference of food odors. Harris G, et al. J Neurosci, 2014 Jul 9. PMID 25009271, Free PMC Article
  2. Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. Styer KL, et al. Science, 2008 Oct 17. PMID 18801967, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Neuropeptide receptor 18
NP_001257083.1
  • Partially confirmed by transcript evidence
NP_001257085.1
  • Partially confirmed by transcript evidence
NP_001257088.1
  • Partially confirmed by transcript evidence
NP_001368133.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    9690745..9696723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001270154.3 → NP_001257083.1  Neuropeptide receptor 18 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257083.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    I2HAC8
    Conserved Domains (1) summary
    cd00637
    Location:50 → 355
    7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

  2. NM_001270156.3 → NP_001257085.1  Neuropeptide receptor 18 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257085.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    I2HAC6, I2HAC8, I2HAC9, I2HAD0, Q09502
    Conserved Domains (1) summary
    cd00637
    Location:63 → 368
    7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

  3. NM_001381071.2 → NP_001368133.1  Neuropeptide receptor 18 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    cd00637
    Location:34 → 339
    7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

  4. NM_001270159.3 → NP_001257088.1  Neuropeptide receptor 18 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257088.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    I2HAC6
    Conserved Domains (1) summary
    cd00637
    Location:63 → 368
    7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein
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