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vps-50 Vps54_N domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 183433, updated on 2-Nov-2024

Summary

Official Symbol
vps-50
Official Full Name
Vps54_N domain-containing protein
Primary source
WormBase:WBGene00008078
Locus tag
CELE_C44B9.1
See related
AllianceGenome:WB:WBGene00008078
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable SNARE binding activity. Involved in positive regulation of dense core granule transport and positive regulation of locomotion involved in locomotory behavior. Predicted to be located in cytosol. Predicted to be part of EARP complex. Is expressed in nervous system. Orthologous to human VPS50 (VPS50 subunit of EARP/GARPII complex). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See vps-50 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (10869193..10874813)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene HECT domain-containing protein Neighboring gene CSD domain-containing protein Neighboring gene Lgl_C domain-containing protein Neighboring gene CUB domain-containing protein Neighboring gene PHD-type domain-containing protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of EARP complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of EARP complex IEA
Inferred from Electronic Annotation
more info
 
part_of EARP complex TAS
Traceable Author Statement
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Vps54_N domain-containing protein
NP_499394.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10869193..10874813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066993.3NP_499394.2  Vps54_N domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499394.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18602
    Conserved Domains (2) summary
    pfam10474
    Location:703953
    DUF2451; Protein of unknown function C-terminus (DUF2451)
    pfam10475
    Location:76363
    DUF2450; Protein of unknown function N-terminal domain (DUF2450)