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rom-2 Inactive rhomboid-related protein 2 [ Caenorhabditis elegans ]

Gene ID: 183564, updated on 2-Nov-2024

Summary

Official Symbol
rom-2
Official Full Name
Inactive rhomboid-related protein 2
Primary source
WormBase:WBGene00004401
Locus tag
CELE_C48B4.2
See related
AllianceGenome:WB:WBGene00004401
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be located in membrane. Orthologous to several human genes including RHBDL3 (rhomboid like 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See rom-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (9593120..9595663, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene putative acyl-coenzyme A oxidase acox-1.5 Neighboring gene Secreted protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Inactive rhomboid-related protein 2
NP_001366679.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    9593120..9595663 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001379864.2NP_001366679.1  Inactive rhomboid-related protein 2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34356
    Conserved Domains (2) summary
    pfam01694
    Location:165311
    Rhomboid; Rhomboid family
    pfam13499
    Location:2182
    EF-hand_7; EF-hand domain pair