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arp-11 Actin-related protein 10 [ Caenorhabditis elegans ]

Gene ID: 183628, updated on 2-Nov-2024

Summary

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Official Symbol
arp-11
Official Full Name
Actin-related protein 10
Primary source
WormBase:WBGene00016793
Locus tag
CELE_C49H3.8
See related
AllianceGenome:WB:WBGene00016793
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in retrograde axonal transport of mitochondrion. Part of dynactin complex. Orthologous to human ACTR10 (actin related protein 10). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See arp-11 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (7900203..7902271, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Bifunctional purine biosynthesis protein ATIC;Phosphoribosylaminoimidazolecarboxamide formyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene lysozyme Neighboring gene Cortactin-binding protein-2 N-terminal domain-containing protein Neighboring gene C3HC-type domain-containing protein Neighboring gene CCR4-NOT transcription complex subunit 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caenorhabditis elegans ortholog of the p24/p22 subunit, DNC-3, is essential for the formation of the dynactin complex by bridging DNC-1/p150(Glued) and DNC-2/dynamitin. Terasawa M, et al. Genes Cells, 2010 Nov. PMID 20964796, Free PMC Article
  2. The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo. Du Z, et al. Dev Cell, 2015 Sep 14. PMID 26321128, Free PMC Article
  3. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  4. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in retrograde axonal transport of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in axon cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
part_of dynactin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of dynactin complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Actin-related protein 10
NP_501314.2
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7900203..7902271 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068913.6 → NP_501314.2  Actin-related protein 10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501314.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9GYR2
    Conserved Domains (1) summary
    cl17037
    Location:3 → 367
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
Nucleotide Protein
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