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scrt-1 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 183848, updated on 2-Nov-2024

Summary

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Official Symbol
scrt-1
Official Full Name
C2H2-type domain-containing protein
Primary source
WormBase:WBGene00016948
Locus tag
CELE_C55C2.1
See related
AllianceGenome:WB:WBGene00016948
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See scrt-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (2568860..2571059)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Sperm-specific class P protein 19 Neighboring gene Amino Acid Transporter Neighboring gene fructose-bisphosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression. Yanai I, et al. Mol Syst Biol, 2008. PMID 18277379, Free PMC Article
  2. FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development. Jin Y, et al. Cancer Lett, 2015 Jun 28. PMID 25827072, Free PMC Article
  3. The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors. Reece-Hoyes JS, et al. Nucleic Acids Res, 2009 Jun. PMID 19372275, Free PMC Article
  4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
C2H2-type domain-containing protein
NP_491001.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    2568860..2571059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058600.3 → NP_491001.2  C2H2-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491001.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01830
    Conserved Domains (3) summary
    sd00017
    Location:96 → 116
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:94 → 116
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:109 → 132
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
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