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trmt-10C.2 tRNA MethylTransferase [ Caenorhabditis elegans ]

Gene ID: 183866, updated on 2-Nov-2024

Summary

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Official Symbol
trmt-10C.2
Official Full Name
tRNA MethylTransferase
Primary source
WormBase:WBGene00016978
Locus tag
CELE_C56G2.3
See related
AllianceGenome:WB:WBGene00016978
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable tRNA binding activity. Predicted to be involved in mitochondrial tRNA 5'-end processing and positive regulation of mitochondrial translation. Predicted to be active in mitochondrion and nucleoplasm. Is expressed in body wall musculature; intestine; nervous system; and pharynx. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See trmt-10C.2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (6346281..6348410)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Proteasomal ubiquitin receptor ADRM1;Proteasomal ubiquitin receptor ADRM1 homolog Neighboring gene DUF4604 domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene KH domain-containing protein akap-1;Tudor domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial S-adenosylmethionine deficiency induces mitochondrial unfolded protein response and extends lifespan in Caenorhabditis elegans. Chen TY, et al. Aging Cell, 2024 Apr. PMID 38361361, Free PMC Article
  2. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
  3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial tRNA 5'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of mitochondrial translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tRNA MethylTransferase
NP_001367605.1
  • Confirmed by transcript evidence;
    Product from WormBase gene class trmt

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6346281..6348410
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001379760.2 → NP_001367605.1  tRNA MethylTransferase [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    cl38912
    Location:186 → 367
    SPOUT_MTase; SPOUT superfamily of SAM-dependent RNA methyltransferases
Nucleotide Protein
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