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timm-17B.2 Translocase, Inner Mitochondrial Membrane [ Caenorhabditis elegans ]

Gene ID: 183965, updated on 2-Nov-2024

Summary

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Official Symbol
timm-17B.2
Official Full Name
Translocase, Inner Mitochondrial Membrane
Primary source
WormBase:WBGene00017069
Locus tag
CELE_D2096.1
See related
AllianceGenome:WB:WBGene00017069
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See timm-17B.2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (8396648..8397954)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene C6 domain-containing protein Neighboring gene GAR domain-containing protein Neighboring gene pseudo Neighboring gene pseudo Neighboring gene F-box domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondria Retrograde Signaling and the UPR mt: Where Are We in Mammals? Arnould T, et al. Int J Mol Sci, 2015 Aug 6. PMID 26258774, Free PMC Article
  2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
contributes_to protein transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein import into mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Translocase, Inner Mitochondrial Membrane
NP_001294049.1
  • Product from WormBase gene class timm;
    Confirmed by transcript evidence
NP_001367715.1
  • Product from WormBase gene class timm;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    8396648..8397954
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001380363.2 → NP_001367715.1  Translocase, Inner Mitochondrial Membrane [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19012
    Conserved Domains (1) summary
    cl02381
    Location:1 → 56
    Tim17; Tim17/Tim22/Tim23/Pmp24 family

  2. NM_001307120.4 → NP_001294049.1  Translocase, Inner Mitochondrial Membrane [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294049.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X5LX78
Nucleotide Protein
Heading Accession and Version

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