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F15D4.4 Peptidase C1A papain C-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 184530, updated on 2-Nov-2024

Summary

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Official Symbol
F15D4.4
Official Full Name
Peptidase C1A papain C-terminal domain-containing protein
Primary source
WormBase:WBGene00008861
Locus tag
CELE_F15D4.4
See related
AllianceGenome:WB:WBGene00008861
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable cysteine-type endopeptidase activator activity involved in apoptotic process and cysteine-type endopeptidase activity. Predicted to be involved in immune response; positive regulation of apoptotic signaling pathway; and proteolysis involved in protein catabolic process. Predicted to be active in extracellular space and lysosome. Is expressed in pharyngeal gland cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F15D4.4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (13239267..13243121, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Cactin_mid domain-containing protein Neighboring gene GQTFVRF-amide Neighboring gene Reactive oxygen species modulator 1 Neighboring gene CCHC-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables cysteine-type endopeptidase activator activity involved in apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cysteine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
  
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis involved in protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Peptidase C1A papain C-terminal domain-containing protein
NP_496805.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13239267..13243121 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064404.9 → NP_496805.3  Peptidase C1A papain C-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496805.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93512
    Conserved Domains (2) summary
    smart00848
    Location:146 → 187
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    cd02248
    Location:227 → 442
    Peptidase_C1A; Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences, ...
Nucleotide Protein
Heading Accession and Version

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