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cdh-8 Cadherin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 184652, updated on 2-Nov-2024

Summary

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Official Symbol
cdh-8
Official Full Name
Cadherin domain-containing protein
Primary source
WormBase:WBGene00017576
Locus tag
CELE_F18F11.3
See related
AllianceGenome:WB:WBGene00017576
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cdh-8 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
26
Sequence:
Chromosome: IV; NC_003282.8 (339808..359293)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Glycosyltransferase family 92 protein Neighboring gene Peroxisomal membrane protein 4 Neighboring gene ncRNA Neighboring gene Calponin-homology (CH) domain-containing protein;FiLamiN (actin binding protein) homolog Neighboring gene ncRNA Neighboring gene Sphingosine-1-phosphate lyase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In situ structure of intestinal apical surface reveals nanobristles on microvilli. Zhu H, et al. Proc Natl Acad Sci U S A, 2022 Jun 14. PMID 35666862, Free PMC Article
  2. Nematode-specific cadherin CDH-8 acts as a receptor for Cry5B toxin in Caenorhabditis elegans. Peng D, et al. Appl Microbiol Biotechnol, 2018 Apr. PMID 29502179
  3. Use of RNAi as a preliminary tool for screening putative receptors of nematicidal toxins from Bacillus thuringiensis. García-Montelongo M, et al. Arch Microbiol, 2021 May. PMID 33432376
  4. The cadherin superfamily. Pettitt J. WormBook, 2005 Dec 29. PMID 18050421, Free PMC Article
  5. Cell adhesion receptors in C. elegans. Cox EA, et al. J Cell Sci, 2004 Apr 15. PMID 15090591

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cadherin domain-containing protein
NP_001294359.1
  • Confirmed by transcript evidence
NP_001294409.1
  • Partially confirmed by transcript evidence
NP_001294410.1
  • Partially confirmed by transcript evidence
NP_001294411.1
  • Partially confirmed by transcript evidence
NP_001294412.1
  • Partially confirmed by transcript evidence
NP_001294413.1
  • Partially confirmed by transcript evidence
NP_001294414.1
  • Partially confirmed by transcript evidence
NP_001294415.1
  • Partially confirmed by transcript evidence
NP_001294416.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    339808..359293
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001307480.3 → NP_001294409.1  Cadherin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294409.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PEK5
    Conserved Domains (1) summary
    cd11304
    Location:552 → 647
    Cadherin_repeat; Cadherin tandem repeat domain

  2. NM_001307483.3 → NP_001294412.1  Cadherin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294412.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PM66
    Conserved Domains (1) summary
    cd11304
    Location:552 → 647
    Cadherin_repeat; Cadherin tandem repeat domain

  3. NM_001307487.3 → NP_001294416.1  Cadherin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294416.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PBR4
    Conserved Domains (1) summary
    cd11304
    Location:552 → 647
    Cadherin_repeat; Cadherin tandem repeat domain

  4. NM_001307484.3 → NP_001294413.1  Cadherin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294413.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PRG1
    Conserved Domains (1) summary
    cd11304
    Location:552 → 647
    Cadherin_repeat; Cadherin tandem repeat domain

  5. NM_001307482.3 → NP_001294411.1  Cadherin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294411.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PBR0
    Conserved Domains (1) summary
    cd11304
    Location:552 → 647
    Cadherin_repeat; Cadherin tandem repeat domain

  6. NM_001307486.4 → NP_001294415.1  Cadherin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294415.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PBD6
    Conserved Domains (1) summary
    cd11304
    Location:552 → 647
    Cadherin_repeat; Cadherin tandem repeat domain

  7. NM_001307481.3 → NP_001294410.1  Cadherin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294410.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PBD1
    Conserved Domains (1) summary
    cd11304
    Location:552 → 647
    Cadherin_repeat; Cadherin tandem repeat domain

  8. NM_001307485.3 → NP_001294414.1  Cadherin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294414.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PEL1
    Conserved Domains (1) summary
    cd11304
    Location:552 → 647
    Cadherin_repeat; Cadherin tandem repeat domain

  9. NM_001307430.3 → NP_001294359.1  Cadherin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294359.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PBI3
Nucleotide Protein
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