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che-7 Innexin [ Caenorhabditis elegans ]

Gene ID: 184979, updated on 2-Nov-2024

Summary

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Official Symbol
che-7
Official Full Name
Innexin
Primary source
WormBase:WBGene00000488
Locus tag
CELE_F26D11.10
See related
AllianceGenome:WB:WBGene00000488
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable gap junction channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in gap junction and plasma membrane. Is expressed in nervous system. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See che-7 in Genome Data Viewer
Location:
chromosome: V
Exon count:
13
Sequence:
Chromosome: V; NC_003283.11 (7961210..7969207, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene C-type lectin domain-containing protein Neighboring gene Coiled-coil domain-containing protein 137 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene PDZ domain-containing protein;Protein lap1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Caenorhabditis elegans INX-4/Innexin is required for the fine-tuning of temperature orientation in thermotaxis behavior. Tsukamoto S, et al. Genes Cells, 2020 Mar. PMID 31917862, Free PMC Article
  2. Differential processing of a chemosensory cue across life stages sharing the same valence state in Caenorhabditis elegans. Banerjee N, et al. Proc Natl Acad Sci U S A, 2023 May 9. PMID 37126715, Free PMC Article
  3. Aversive Behavior in the Nematode C. elegans Is Modulated by cGMP and a Neuronal Gap Junction Network. Krzyzanowski MC, et al. PLoS Genet, 2016 Jul. PMID 27459302, Free PMC Article
  4. Interactions between innexins UNC-7 and UNC-9 mediate electrical synapse specificity in the Caenorhabditis elegans locomotory nervous system. Starich TA, et al. Neural Dev, 2009 May 11. PMID 19432959, Free PMC Article
  5. A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans. Kaplan JM, et al. Proc Natl Acad Sci U S A, 1993 Mar 15. PMID 8460126, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in gap junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in gap junction IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Innexin
NP_001309632.1
  • Confirmed by transcript evidence
NP_001309634.1
  • Confirmed by transcript evidence
NP_001309635.1
  • Confirmed by transcript evidence
NP_001317771.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    7961210..7969207 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001322573.3 → NP_001309635.1  Innexin [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MBM6
    Conserved Domains (1) summary
    pfam00876
    Location:58 → 421
    Innexin; Innexin

  2. NM_001322572.2 → NP_001309634.1  Innexin [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MB33
    Conserved Domains (1) summary
    pfam00876
    Location:58 → 421
    Innexin; Innexin

  3. NM_001330873.2 → NP_001317771.1  Innexin [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MB60

  4. NM_001322574.2 → NP_001309632.1  Innexin [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A131MBQ3
    Conserved Domains (1) summary
    pfam00876
    Location:61 → 424
    Innexin; Innexin
Nucleotide Protein
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