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acl-11 Phospholipid/glycerol acyltransferase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 185044, updated on 2-Nov-2024

Summary

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Official Symbol
acl-11
Official Full Name
Phospholipid/glycerol acyltransferase domain-containing protein
Primary source
WormBase:WBGene00017888
Locus tag
CELE_F28B3.9
See related
AllianceGenome:WB:WBGene00017888
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum and mitochondrion. Orthologous to human AGPAT5 (1-acylglycerol-3-phosphate O-acyltransferase 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See acl-11 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003279.8 (4928507..4932175)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Transmembrane protein 230 Neighboring gene Importin N-terminal domain-containing protein Neighboring gene Major Facilitator Superfamily Domain containing homolog Neighboring gene AMP-dependent synthetase/ligase domain-containing protein;DMAP1-binding domain-containing protein Neighboring gene Chloride channel protein CLC-d Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  2. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
  3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphatidylinositol acyl-chain remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Phospholipid/glycerol acyltransferase domain-containing protein
NP_491479.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    4928507..4932175
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059078.5 → NP_491479.2  Phospholipid/glycerol acyltransferase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491479.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95R12
    Conserved Domains (2) summary
    cd07990
    Location:63 → 273
    LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
    pfam16076
    Location:266 → 309
    Acyltransf_C; Acyltransferase C-terminus
Nucleotide Protein
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