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thn-1 Pathogenesis-related protein 5-like [ Caenorhabditis elegans ]

Gene ID: 185060, updated on 2-Nov-2024

Summary

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Official Symbol
thn-1
Official Full Name
Pathogenesis-related protein 5-like
Primary source
WormBase:WBGene00009213
Locus tag
CELE_F28D1.3
See related
AllianceGenome:WB:WBGene00009213
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See thn-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
2
Sequence:
Chromosome: IV; NC_003282.8 (12380084..12380900)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene WD repeat-containing protein 46 Neighboring gene Protein atz-1 Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Pathogenesis-related protein 5-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses. Pukkila-Worley R, et al. PLoS Pathog, 2011 Jun. PMID 21731485, Free PMC Article
  2. Components of the cultivated red seaweed Chondrus crispus enhance the immune response of Caenorhabditis elegans to Pseudomonas aeruginosa through the pmk-1, daf-2/daf-16, and skn-1 pathways. Liu J, et al. Appl Environ Microbiol, 2013 Dec. PMID 24056462, Free PMC Article
  3. Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity. Cui Y, et al. Genome Biol, 2007. PMID 17592649, Free PMC Article
  4. Transcriptional responses to pathogens in Caenorhabditis elegans. Shivers RP, et al. Curr Opin Microbiol, 2008 Jun. PMID 18567532, Free PMC Article
  5. Genome-wide microarrray analysis reveals roles for the REF-1 family member HLH-29 in ferritin synthesis and peroxide stress response. Quach TK, et al. PLoS One, 2013. PMID 23533643, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in innate immune response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
Pathogenesis-related protein 5-like
NP_502360.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12380084..12380900
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069959.3 → NP_502360.1  Pathogenesis-related protein 5-like [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502360.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19874
    Conserved Domains (1) summary
    cd09218
    Location:21 → 233
    TLP-PA; allergenic/antifungal thaumatin-like proteins: plant and animal homologs
Nucleotide Protein
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