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phm-2 Pharyngeal muscle protein 2 [ Caenorhabditis elegans ]

Gene ID: 185193, updated on 2-Nov-2024

Summary

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Official Symbol
phm-2
Official Full Name
Pharyngeal muscle protein 2
Primary source
WormBase:WBGene00009314
Locus tag
CELE_F32B4.4
See related
AllianceGenome:WB:WBGene00009314
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of mRNA processing and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including body wall musculature; intestine; pharynx; somatic nervous system; and vulva. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See phm-2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
9
Sequence:
Chromosome: I; NC_003279.8 (11517558..11526797)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Nucleotide-diphospho-sugar transferase domain-containing protein Neighboring gene Peroxisome biogenesis protein 3-2-like Neighboring gene AB hydrolase-1 domain-containing protein Neighboring gene HSF_DOMAIN domain-containing protein;Zeta_toxin domain-containing protein Neighboring gene ncRNA Neighboring gene Dystrophin;Dystrophin-1 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caenorhabditis elegans is a model host for Salmonella typhimurium. Labrousse A, et al. Curr Biol, 2000 Nov 30. PMID 11114526
  2. Caenorhabditis elegans: plague bacteria biofilm blocks food intake. Darby C, et al. Nature, 2002 May 16. PMID 12015591
  3. A liquid-based method for the assessment of bacterial pathogenicity using the nematode Caenorhabditis elegans. Smith MP, et al. FEMS Microbiol Lett, 2002 May 7. PMID 12044672
  4. Killing of Caenorhabditis elegans by Burkholderia cepacia is controlled by the cep quorum-sensing system. Köthe M, et al. Cell Microbiol, 2003 May. PMID 12713492
  5. Live and dead GFP-tagged bacteria showed indistinguishable fluorescence in Caenorhabditis elegans gut. Hsiao JY, et al. J Microbiol, 2013 Jun. PMID 23812817

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in digestion IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of mRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pharyngeal muscle protein 2
NP_001021440.2
  • Confirmed by transcript evidence
NP_001251667.1
  • Confirmed by transcript evidence
NP_001379397.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    11517558..11526797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026269.4 → NP_001021440.2  Pharyngeal muscle protein 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021440.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F5GUF6, O62203, Q7Z0X2
    Conserved Domains (2) summary
    smart00513
    Location:9 → 43
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd12417
    Location:397 → 474
    RRM_SAFB_like; RNA recognition motif (RRM) found in the scaffold attachment factor (SAFB) family

  2. NM_001392949.1 → NP_001379397.1  Pharyngeal muscle protein 2 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    cl17169
    Location:4 → 64
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. NM_001264738.3 → NP_001251667.1  Pharyngeal muscle protein 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001251667.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F5GUF6
    Conserved Domains (1) summary
    cd12417
    Location:326 → 403
    RRM_SAFB_like; RNA recognition motif in the scaffold attachment factor (SAFB) family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O62203.3

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