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F36A2.2 tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)] [ Caenorhabditis elegans ]

Gene ID: 185334, updated on 2-Nov-2024

Summary

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Official Symbol
F36A2.2
Official Full Name
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]
Primary source
WormBase:WBGene00009452
Locus tag
CELE_F36A2.2
See related
AllianceGenome:WB:WBGene00009452
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable tRNA dihydrouridine synthase activity. Predicted to be involved in tRNA dihydrouridine synthesis. Orthologous to human DUS1L (dihydrouridine synthase 1 like). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F36A2.2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
12
Sequence:
Chromosome: I; NC_003279.8 (8801612..8804697, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Disintegrin and metalloproteinase domain-containing protein 10 homolog Neighboring gene Malate dehydrogenase Neighboring gene CID domain-containing protein Neighboring gene 14 kDa phosphohistidine phosphatase-like Neighboring gene Fibronectin type-III domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA dihydrouridine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in tRNA dihydrouridine synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]
NP_492379.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    8801612..8804697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059978.2 → NP_492379.1  tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)] [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492379.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XVN8
    Conserved Domains (2) summary
    COG0042
    Location:61 → 375
    DusA; tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]
    cd02801
    Location:74 → 298
    DUS_like_FMN; Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also ...
Nucleotide Protein
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