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F44E7.9 Rab5-interacting protein [ Caenorhabditis elegans ]

Gene ID: 185741, updated on 2-Nov-2024

Summary

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Official Symbol
F44E7.9
Official Full Name
Rab5-interacting protein
Primary source
WormBase:WBGene00018431
Locus tag
CELE_F44E7.9
See related
AllianceGenome:WB:WBGene00018431
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mitochondrial respirasome assembly. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 2. Orthologous to human RAB5IF (RAB5 interacting factor). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F44E7.9 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (5791230..5792229)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene Nuclear Hormone Receptor family Neighboring gene ncRNA Neighboring gene N-acetylgalactosaminide beta-1,3-galactosyltransferase Neighboring gene UDP-galactose transporter Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in cellular component organization IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial respirasome assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Rab5-interacting protein
NP_504519.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    5791230..5792229
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072118.5 → NP_504519.1  Rab5-interacting protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504519.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16254
    Conserved Domains (1) summary
    pfam07019
    Location:36 → 112
    Rab5ip; Rab5-interacting protein (Rab5ip)
Nucleotide Protein
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