U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

sra-13 Serpentine receptor class alpha-13 [ Caenorhabditis elegans ]

Gene ID: 186058, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
sra-13
Official Full Name
Serpentine receptor class alpha-13
Primary source
WormBase:WBGene00005039
Locus tag
CELE_F49E12.5
See related
AllianceGenome:WB:WBGene00005039
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables olfactory receptor activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception of smell; negative regulation of Ras protein signal transduction; and negative regulation of vulval development. Predicted to be located in membrane. Is expressed in several structures, including amphid neurons; body wall musculature; head; hypodermis; and muscle cell. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See sra-13 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (8407685..8409237)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Peroxidase skpo-1 Neighboring gene UBC core domain-containing protein Neighboring gene Transcription factor efl-3 Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. C. elegans-based chemosensation strategy for the early detection of cancer metabolites in urine samples. Lanza E, et al. Sci Rep, 2021 Aug 24. PMID 34429473, Free PMC Article
  2. The putative chemoreceptor families of C. elegans. Robertson HM, et al. WormBook, 2006 Jan 6. PMID 18050473, Free PMC Article
  3. G Proteins and GPCRs in C. elegans Development: A Story of Mutual Infidelity. Matúš D, et al. J Dev Biol, 2018 Nov 25. PMID 30477278, Free PMC Article
  4. Caenorhabditis elegans integrates the signals of butanone and food to enhance chemotaxis to butanone. Torayama I, et al. J Neurosci, 2007 Jan 24. PMID 17251413, Free PMC Article
  5. The C. elegans G-protein-coupled receptor SRA-13 inhibits RAS/MAPK signalling during olfaction and vulval development. Battu G, et al. Development, 2003 Jun. PMID 12736202

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in detection of chemical stimulus involved in sensory perception IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in detection of chemical stimulus involved in sensory perception of smell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of Ras protein signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of response to food IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of vulval development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to stimulus IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of chemical stimulus IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IC
Inferred by Curator
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Serpentine receptor class alpha-13
NP_001022186.1
  • Partially confirmed by transcript evidence
NP_001022187.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8407685..8409237
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027016.3 → NP_001022187.1  Serpentine receptor class alpha-13 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022187.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q20618
    Conserved Domains (1) summary
    pfam02117
    Location:23 → 170
    7TM_GPCR_Sra; Serpentine type 7TM GPCR chemoreceptor Sra

  2. NM_001027015.1 → NP_001022186.1  Serpentine receptor class alpha-13 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022186.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q20618, Q7JM75
    Conserved Domains (1) summary
    pfam02117
    Location:8 → 334
    7TM_GPCR_Sra; Serpentine type 7TM GPCR chemoreceptor Sra
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q20618.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools