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F58G11.4 MFS domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 186546, updated on 2-Nov-2024

Summary

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Official Symbol
F58G11.4
Official Full Name
MFS domain-containing protein
Primary source
WormBase:WBGene00010282
Locus tag
CELE_F58G11.4
See related
AllianceGenome:WB:WBGene00010282
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in lysosomal membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Orthologous to human MFSD8 (major facilitator superfamily domain containing 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F58G11.4 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (13672589..13676064)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DEAD-box ATP-dependent RNA helicase rde-12 Neighboring gene HTH OST-type domain-containing protein Neighboring gene CID domain-containing protein Neighboring gene Vacuolar fusion protein CCZ1 homolog Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
MFS domain-containing protein
NP_001256536.2
  • Confirmed by transcript evidence
NP_001256537.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    13672589..13676064
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269607.3 → NP_001256536.2  MFS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256536.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XVL9
    Conserved Domains (2) summary
    cd06174
    Location:12 → 446
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:19 → 334
    MFS_1; Major Facilitator Superfamily

  2. NM_001269608.4 → NP_001256537.2  MFS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256537.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    D9N145
    Conserved Domains (1) summary
    cd06174
    Location:1 → 366
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
Nucleotide Protein
Heading Accession and Version

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