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slcf-1 MFS domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 186633, updated on 2-Nov-2024

Summary

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Official Symbol
slcf-1
Official Full Name
MFS domain-containing protein
Primary source
WormBase:WBGene00010340
Locus tag
CELE_F59F5.1
See related
AllianceGenome:WB:WBGene00010340
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Located in basolateral plasma membrane. Is expressed in intestine. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See slcf-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (10529294..10533040)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Lysophospholipid acyltransferase 7 Neighboring gene Arf-GAP domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Gut granule LOss Neighboring gene Protein kinase domain-containing protein Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. μHigh resolution-magic-angle spinning NMR spectroscopy for metabolic phenotyping of Caenorhabditis elegans. Wong A, et al. Anal Chem, 2014 Jun 17. PMID 24897622
  2. Metabolomics analysis uncovers that dietary restriction buffers metabolic changes associated with aging in Caenorhabditis elegans. Pontoizeau C, et al. J Proteome Res, 2014 Jun 6. PMID 24819046, Free PMC Article
  3. [Metabolic homeostasis as the cornerstone of aging]. Terret C, et al. Med Sci (Paris), 2012 Mar. PMID 22480656
  4. Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans. Mouchiroud L, et al. Aging Cell, 2011 Feb. PMID 21040400
  5. AP-1 Recruits SMAP-1/SMAPs to the trans-Golgi Network to Promote Sorting in Polarized Epithelia. Wang S, et al. Front Cell Dev Biol, 2021. PMID 34901019, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables monocarboxylic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monocarboxylic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in basolateral plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MFS domain-containing protein
NP_509762.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    10529294..10533040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077361.5 → NP_509762.2  MFS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509762.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ECR3
    Conserved Domains (2) summary
    cd06174
    Location:44 → 410
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:79 → 376
    MFS_1; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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