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scl-12 SCP domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 186714, updated on 2-Nov-2024

Summary

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Official Symbol
scl-12
Official Full Name
SCP domain-containing protein
Primary source
WormBase:WBGene00019178
Locus tag
CELE_H10D18.2
See related
AllianceGenome:WB:WBGene00019178
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in extracellular space. Orthologous to several human genes including PI15 (peptidase inhibitor 15). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See scl-12 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (3812591..3813437)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene SCP domain-containing protein Neighboring gene FERM domain-containing protein;SCP domain-containing protein Neighboring gene Retrotransposon gag protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mobilization of cholesterol induces the transition from quiescence to growth in Caenorhabditis elegans through steroid hormone and mTOR signaling. Schmeisser K, et al. Commun Biol, 2024 Jan 24. PMID 38267699, Free PMC Article
  2. Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. Crawford ED, et al. Cell Death Differ, 2012 Dec. PMID 22918439, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SCP domain-containing protein
NP_504056.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    3812591..3813437
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071655.3 → NP_504056.1  SCP domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504056.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N5N3
    Conserved Domains (1) summary
    smart00198
    Location:21 → 175
    SCP; SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains
Nucleotide Protein
Heading Accession and Version

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