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H20J04.4 RNA helicase [ Caenorhabditis elegans ]

Gene ID: 186756, updated on 2-Nov-2024

Summary

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Official Symbol
H20J04.4
Official Full Name
RNA helicase
Primary source
WormBase:WBGene00019219
Locus tag
CELE_H20J04.4
See related
AllianceGenome:WB:WBGene00019219
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Predicted to be involved in rRNA processing. Predicted to be located in P granule. Predicted to be active in nucleus. Orthologous to human DDX49 (DEAD-box helicase 49). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See H20J04.4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (4329016..4334647)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene putative U2 small nuclear ribonucleoprotein A' Neighboring gene Prefoldin subunit 2 Neighboring gene Alcohol dehydrogenase transcription factor myb/sant-like protein Neighboring gene Bromodomain adjacent to zinc finger domain protein 1A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in P granule IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA helicase
NP_001040788.1
  • Partially confirmed by transcript evidence
NP_001040789.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    4329016..4334647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047324.4 → NP_001040789.1  RNA helicase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040789.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2WF63
    Conserved Domains (3) summary
    COG0513
    Location:69 → 546
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd00268
    Location:91 → 295
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam00271
    Location:333 → 432
    Helicase_C; Helicase conserved C-terminal domain

  2. NM_001047323.3 → NP_001040788.1  RNA helicase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040788.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N5M1
    Conserved Domains (3) summary
    smart00487
    Location:104 → 311
    DEXDc; DEAD-like helicases superfamily
    cd00268
    Location:91 → 295
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam00271
    Location:333 → 432
    Helicase_C; Helicase conserved C-terminal domain
Nucleotide Protein
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