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M02B7.2 Exonuclease domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 187397, updated on 2-Nov-2024

Summary

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Official Symbol
M02B7.2
Official Full Name
Exonuclease domain-containing protein
Primary source
WormBase:WBGene00019724
Locus tag
CELE_M02B7.2
See related
AllianceGenome:WB:WBGene00019724
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to be involved in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be active in cytoplasm. Orthologous to human ERI3 (ERI1 exoribonuclease family member 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See M02B7.2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (3803581..3804949)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ShKT domain-containing protein Neighboring gene Osmotic avoidance abnormal protein 3 Neighboring gene UDP-N-acetylglucosamine transferase subunit ALG14 Neighboring gene ncRNA Neighboring gene FTH domain-containing protein Neighboring gene DUF1014-domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables exonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Exonuclease domain-containing protein
NP_001368212.1
  • Confirmed by transcript evidence
NP_500418.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    3803581..3804949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068017.4 → NP_500418.1  Exonuclease domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500418.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q94285
    Conserved Domains (1) summary
    cd06133
    Location:61 → 240
    ERI-1_3'hExo_like; DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins

  2. NM_001380165.1 → NP_001368212.1  Exonuclease domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PLK4
    Conserved Domains (1) summary
    cd06133
    Location:2 → 163
    ERI-1_3'hExo_like; DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins
Nucleotide Protein
Heading Accession and Version

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