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glt-6 Putative sodium-dependent excitatory amino acid transporter glt-6 [ Caenorhabditis elegans ]

Gene ID: 187623, updated on 2-Nov-2024

Summary

Official Symbol
glt-6
Official Full Name
Putative sodium-dependent excitatory amino acid transporter glt-6
Primary source
WormBase:WBGene00001624
Locus tag
CELE_R05G6.6
See related
AllianceGenome:WB:WBGene00001624
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in excretory cell and marginal cell. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 41. Orthologous to human SLC1A2 (solute carrier family 1 member 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See glt-6 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (7503622..7506447)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene EGF-like domain-containing protein Neighboring gene Otopetrin-2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative voltage-dependent anion-selective channel Neighboring gene Uroporphyrinogen-III synthase Neighboring gene Phosphoinositide phospholipase C Neighboring gene ncRNA

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables L-glutamate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glutamate:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables neutral L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in L-glutamate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neutral amino acid transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Putative sodium-dependent excitatory amino acid transporter glt-6
NP_501210.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7503622..7506447
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068809.10NP_501210.3  Putative sodium-dependent excitatory amino acid transporter glt-6 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501210.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q21751
    Conserved Domains (1) summary
    pfam00375
    Location:18448
    SDF; Sodium:dicarboxylate symporter family