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fil-1 Lipase [ Caenorhabditis elegans ]

Gene ID: 187940, updated on 2-Nov-2024

Summary

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Official Symbol
fil-1
Official Full Name
Lipase
Primary source
WormBase:WBGene00011321
Locus tag
CELE_T01C3.4
See related
AllianceGenome:WB:WBGene00011321
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables lipase activity. Involved in lipid catabolic process. Is expressed in intestine. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See fil-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (14993838..14995207)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Transcription and mRNA export factor ENY2 Neighboring gene RING-type domain-containing protein Neighboring gene Receptor L-domain domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Toxic Effects of Size-tunable Gold Nanoparticles on Caenorhabditis elegans Development and Gene Regulation. Hu CC, et al. Sci Rep, 2018 Oct 15. PMID 30323250, Free PMC Article
  2. IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Jo H, et al. Cell Metab, 2009 May. PMID 19416714
  3. Cytochrome P450s and short-chain dehydrogenases mediate the toxicogenomic response of PCB52 in the nematode Caenorhabditis elegans. Menzel R, et al. J Mol Biol, 2007 Jun 29. PMID 17499272
  4. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables lipase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in lipid catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Lipase
NP_506688.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    14993838..14995207
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074287.5 → NP_506688.1  Lipase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506688.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22060
    Conserved Domains (1) summary
    pfam01674
    Location:67 → 317
    Lipase_2; Lipase (class 2)
Nucleotide Protein
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