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T12E12.6 Peptidase_M1 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 188454, updated on 2-Nov-2024

Summary

Official Symbol
T12E12.6
Official Full Name
Peptidase_M1 domain-containing protein
Primary source
WormBase:WBGene00020465
Locus tag
CELE_T12E12.6
See related
AllianceGenome:WB:WBGene00020465
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Involved in embryo development; regulation of egg-laying behavior; and regulation of meiotic cell cycle process involved in oocyte maturation. Predicted to be active in cytoplasm; extracellular space; and membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See T12E12.6 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
9
Sequence:
Chromosome: IV; NC_003282.8 (5567020..5574133, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metalloaminopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptide binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in embryo development ending in birth or egg hatching IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in peptide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of egg-laying behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of egg-laying behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of meiotic cell cycle process involved in oocyte maturation IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Peptidase_M1 domain-containing protein
NP_500831.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    5567020..5574133 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068430.4NP_500831.2  Peptidase_M1 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500831.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A5A631, G4SGR0
    Conserved Domains (1) summary
    cl14813
    Location:25402
    GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)