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T21D12.12 BPTI/Kunitz inhibitor domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 188695, updated on 2-Nov-2024

Summary

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Official Symbol
T21D12.12
Official Full Name
BPTI/Kunitz inhibitor domain-containing protein
Primary source
WormBase:WBGene00020651
Locus tag
CELE_T21D12.12
See related
AllianceGenome:WB:WBGene00020651
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See T21D12.12 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (266448..268322)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene WW domain-containing protein Neighboring gene Paralyzed arrest at two-fold protein 6 Neighboring gene Serine/threonine-protein kinase DDB_G0282963 Neighboring gene Serpentine Receptor, class H

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
BPTI/Kunitz inhibitor domain-containing protein
NP_499892.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    266448..268322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067491.7 → NP_499892.1  BPTI/Kunitz inhibitor domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499892.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16784
    Conserved Domains (2) summary
    cd00109
    Location:127 → 183
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    pfam00014
    Location:23 → 77
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
Nucleotide Protein
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