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T24C4.5 DNA primase [ Caenorhabditis elegans ]

Gene ID: 188846, updated on 2-Nov-2024

Summary

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Official Symbol
T24C4.5
Official Full Name
DNA primase
Primary source
WormBase:WBGene00020761
Locus tag
CELE_T24C4.5
See related
AllianceGenome:WB:WBGene00020761
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA primase activity. Predicted to be involved in DNA replication, synthesis of primer. Predicted to be part of alpha DNA polymerase:primase complex. Orthologous to human PRIM1 (DNA primase subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See T24C4.5 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (877435..879734, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein DPCD Neighboring gene DUF2975 domain-containing protein Neighboring gene Transmembrane protein 225 Neighboring gene Peptidase M16 N-terminal domain-containing protein Neighboring gene Zyg eleven-related protein 1 Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA primase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA primase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA replication, synthesis of primer IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA replication, synthesis of primer IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of DNA-directed RNA polymerase complex IEA
Inferred from Electronic Annotation
more info
  
part_of alpha DNA polymerase:primase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of primosome complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA primase
NP_001379895.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    877435..879734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001393269.1 → NP_001379895.1  DNA primase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TZ34
    Conserved Domains (1) summary
    cd04860
    Location:21 → 215
    AE_Prim_S; primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. Primases are DNA-dependent RNA polymerases which synthesis the short RNA primers required for DNA replication. In addition to its catalytic role in ...
Nucleotide Protein
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