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gst-13 Glutathione S-transferase [ Caenorhabditis elegans ]

Gene ID: 188915, updated on 2-Nov-2024

Summary

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Official Symbol
gst-13
Official Full Name
Glutathione S-transferase
Primary source
WormBase:WBGene00001761
Locus tag
CELE_T26C5.1
See related
AllianceGenome:WB:WBGene00001761
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glutathione transferase activity. Involved in innate immune response. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See gst-13 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (9231457..9232344)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene Apple domain-containing protein Neighboring gene Acetyl-coenzyme A transporter 1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A proteomics approach to quantify protein levels following RNA interference: case study with glutathione transferase superfamily from the model metazoan Caenorhabditis elegans. Lacourse EJ, et al. J Proteome Res, 2008 Aug. PMID 18582093
  2. Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal. Ayyadevara S, et al. Mech Ageing Dev, 2007 Feb. PMID 17157356, Free PMC Article
  3. p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. Troemel ER, et al. PLoS Genet, 2006 Nov 10. PMID 17096597, Free PMC Article
  4. Development of a transcription-based bioanalytical tool to quantify the toxic potencies of hydrophilic compounds in water using the nematode Caenorhabditis elegans. Karengera A, et al. Ecotoxicol Environ Saf, 2021 Dec 20. PMID 34700171
  5. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables glutathione transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutathione transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in innate immune response HEP PubMed 

General protein information

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Preferred Names
Glutathione S-transferase
NP_495967.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    9231457..9232344
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063566.7 → NP_495967.1  Glutathione S-transferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495967.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22814
    Conserved Domains (3) summary
    PTZ00057
    Location:6 → 208
    PTZ00057; glutathione s-transferase; Provisional
    cd03192
    Location:83 → 190
    GST_C_Sigma_like; C-terminal, alpha helical domain of Class Sigma-like Glutathione S-transferases
    cd03039
    Location:4 → 73
    GST_N_Sigma_like; GST_N family, Class Sigma_like; composed of GSTs belonging to class Sigma and similar proteins, including GSTs from class Mu, Pi and Alpha. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of ...
Nucleotide Protein
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