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T27E4.1 C2 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 188995, updated on 2-Nov-2024

Summary

Official Symbol
T27E4.1
Official Full Name
C2 domain-containing protein
Primary source
WormBase:WBGene00020861
Locus tag
CELE_T27E4.1
See related
AllianceGenome:WB:WBGene00020861
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable SNARE binding activity; calcium ion sensor activity; and calcium-dependent phospholipid binding activity. Predicted to be involved in calcium-dependent activation of synaptic vesicle fusion; regulation of calcium ion-dependent exocytosis; and vesicle fusion. Predicted to be active in several cellular components, including axon; exocytic vesicle; and synapse. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See T27E4.1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (9092345..9094357)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 3-hydroxyacyl-CoA dehydrogenase NAD binding domain-containing protein Neighboring gene N-acetyltransferase domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium ion sensor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium-dependent phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in calcium-dependent activation of synaptic vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of calcium ion-dependent exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in exocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
C2 domain-containing protein
NP_505358.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    9092345..9094357
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072957.4NP_505358.1  C2 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505358.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23056
    Conserved Domains (1) summary
    cl14603
    Location:172304
    C2; C2 domain