U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

hic-1 Lens fiber membrane intrinsic protein [ Caenorhabditis elegans ]

Gene ID: 189029, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
hic-1
Official Full Name
Lens fiber membrane intrinsic protein
Primary source
WormBase:WBGene00020887
Locus tag
CELE_T28B4.4
See related
AllianceGenome:WB:WBGene00020887
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Is expressed in cholinergic neurons; head; tail; and ventral nerve cord. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See hic-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
4
Sequence:
Chromosome: X; NC_003284.9 (6597979..6598708, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene F-box domain-containing protein Neighboring gene ncRNA Neighboring gene tRNA-Phe Neighboring gene Transthyretin-like family protein Neighboring gene tRNA Neighboring gene tRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Wnt Secretion Is Regulated by the Tetraspan Protein HIC-1 through Its Interaction with Neurabin/NAB-1. Tikiyani V, et al. Cell Rep, 2018 Nov 13. PMID 30428353, Free PMC Article
  2. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. HIC-1 affects Wnt secretion by modulating the actin cytoskeleton through its interaction with the actin-binding protein NAB-1.
    Title: Wnt Secretion Is Regulated by the Tetraspan Protein HIC-1 through Its Interaction with Neurabin/NAB-1.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Lens fiber membrane intrinsic protein
NP_509111.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    6597979..6598708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076710.8 → NP_509111.3  Lens fiber membrane intrinsic protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509111.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17346
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools