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angl-1 Endonuclease/exonuclease/phosphatase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 189127, updated on 2-Nov-2024

Summary

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Official Symbol
angl-1
Official Full Name
Endonuclease/exonuclease/phosphatase domain-containing protein
Primary source
WormBase:WBGene00020955
Locus tag
CELE_W02G9.5
See related
AllianceGenome:WB:WBGene00020955
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable mRNA 3'-UTR binding activity. Is expressed in several structures, including ganglia; intestine; pharyngeal muscle cell; postcloacal sensillum; and ventral cord neurons. Orthologous to human ANGEL1 (angel homolog 1) and ANGEL2 (angel homolog 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See angl-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
8
Sequence:
Chromosome: V; NC_003283.11 (2653083..2662655)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene SOCS box domain-containing protein Neighboring gene ncRNA Neighboring gene Triokinase/FMN cyclase Neighboring gene ncRNA Neighboring gene Putative nudix hydrolase 2 Neighboring gene tRNA-Thr Neighboring gene ncRNA Neighboring gene CUB domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Ccr4-Not deadenylase complex constitutes the main poly(A) removal activity in C. elegans. Nousch M, et al. J Cell Sci, 2013 Sep 15. PMID 23843623
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Endonuclease/exonuclease/phosphatase domain-containing protein
NP_001303707.1
  • Partially confirmed by transcript evidence
NP_001303752.1
  • Confirmed by transcript evidence
NP_001364845.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    2653083..2662655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001316778.3 → NP_001303707.1  Endonuclease/exonuclease/phosphatase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0M9JJ86
    Conserved Domains (1) summary
    cl00490
    Location:280 → 478
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

  2. NM_001377589.2 → NP_001364845.1  Endonuclease/exonuclease/phosphatase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0M7RFG6
    Conserved Domains (1) summary
    cl00490
    Location:214 → 412
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

  3. NM_001316823.4 → NP_001303752.1  Endonuclease/exonuclease/phosphatase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0M7RDV8
    Conserved Domains (1) summary
    cl00490
    Location:75 → 273
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
Nucleotide Protein
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