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W03A5.6 NET domain-containing protein;Protein kinase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 189142, updated on 2-Nov-2024

Summary

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Official Symbol
W03A5.6
Official Full Name
NET domain-containing protein;Protein kinase domain-containing protein
Primary source
WormBase:WBGene00020970
Locus tag
CELE_W03A5.6
See related
AllianceGenome:WB:WBGene00020970
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable molecular adaptor activity. Predicted to be involved in modulation of chemical synaptic transmission. Predicted to be active in glutamatergic synapse and postsynaptic specialization. Orthologous to several human genes including DLGAP1 (DLG associated protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See W03A5.6 in Genome Data Viewer
Location:
chromosome: III
Exon count:
12
Sequence:
Chromosome: III; NC_003281.10 (5431379..5440640, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein Neighboring gene Ground-like domain-containing protein Neighboring gene ncRNA Neighboring gene J domain-containing protein Neighboring gene DM2 domain-containing protein Neighboring gene DIS3-like exonuclease 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
  2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in modulation of chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signaling IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in glutamatergic synapse IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in postsynaptic specialization IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
NET domain-containing protein;Protein kinase domain-containing protein
NP_001337303.1
  • Confirmed by transcript evidence
NP_001337304.1
  • Partially confirmed by transcript evidence
NP_498156.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5431379..5440640 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001350343.3 → NP_001337303.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1T5HUK8
    Conserved Domains (1) summary
    pfam03359
    Location:444 → 586
    GKAP; Guanylate-kinase-associated protein (GKAP) protein

  2. NM_001350344.3 → NP_001337304.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1T5HV05
    Conserved Domains (1) summary
    pfam03359
    Location:446 → 588
    GKAP; Guanylate-kinase-associated protein (GKAP) protein

  3. NM_065755.5 → NP_498156.1  NET domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498156.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23138
    Conserved Domains (1) summary
    pfam03359
    Location:147 → 286
    GKAP; Guanylate-kinase-associated protein (GKAP) protein
Nucleotide Protein
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