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frpr-19 G-protein coupled receptors family 1 profile domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 189817, updated on 2-Nov-2024

Summary

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Official Symbol
frpr-19
Official Full Name
G-protein coupled receptors family 1 profile domain-containing protein
Primary source
WormBase:WBGene00021510
Locus tag
CELE_Y41D4A.8
See related
AllianceGenome:WB:WBGene00021510
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See frpr-19 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (1775181..1781659, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene EGF-like domain-containing protein Neighboring gene ncRNA Neighboring gene Transmembrane protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Signaling via the FLP-14/FRPR-19 neuropeptide pathway sustains nociceptive response to repeated noxious stimuli in C. elegans. Marques F, et al. PLoS Genet, 2021 Nov. PMID 34748554, Free PMC Article
  2. The neuropeptidergic connectome of C. elegans. Ripoll-Sánchez L, et al. Neuron, 2023 Nov 15. PMID 37935195, Free PMC Article
  3. System-wide mapping of peptide-GPCR interactions in C. elegans. Beets I, et al. Cell Rep, 2023 Sep 26. PMID 37656621, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Signaling via the FLP-14/FRPR-19 neuropeptide pathway sustains nociceptive response to repeated noxious stimuli in C. elegans.
    Title: Signaling via the FLP-14/FRPR-19 neuropeptide pathway sustains nociceptive response to repeated noxious stimuli in C. elegans.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables neuropeptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in neuropeptide signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
G-protein coupled receptors family 1 profile domain-containing protein
NP_001294552.1
  • Confirmed by transcript evidence
NP_001370911.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    1775181..1781659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001307623.5 → NP_001294552.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294552.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PC84
    Conserved Domains (1) summary
    cd14978
    Location:64 → 363
    7tmA_FMRFamide_R-like; FMRFamide (Phe-Met-Arg-Phe) receptors and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. NM_001383044.2 → NP_001370911.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PMM5
    Conserved Domains (1) summary
    cd14978
    Location:64 → 363
    7tmA_FMRFamide_R-like; FMRFamide (Phe-Met-Arg-Phe) receptors and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
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