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icap-1 Integrin Cytoplasmic domain-Associated Protein homolog [ Caenorhabditis elegans ]

Gene ID: 189926, updated on 2-Nov-2024

Summary

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Official Symbol
icap-1
Official Full Name
Integrin Cytoplasmic domain-Associated Protein homolog
Primary source
WormBase:WBGene00012889
Locus tag
CELE_Y45F10D.10
See related
AllianceGenome:WB:WBGene00012889
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in integrin-mediated signaling pathway. Orthologous to human ITGB1BP1 (integrin subunit beta 1 binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See icap-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (13785743..13786961, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Putative polypeptide N-acetylgalactosaminyltransferase 10;Ricin B lectin domain-containing protein Neighboring gene Beta-lactamase-related domain-containing protein Neighboring gene NIF system FeS cluster assembly NifU N-terminal domain-containing protein Neighboring gene Spindle assembly abnormal protein 6 Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Chapman EM, et al. Nat Commun, 2019 Apr 17. PMID 30996251, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Integrin Cytoplasmic domain-Associated Protein homolog
NP_001255757.1
  • Confirmed by transcript evidence;
    Product from WormBase gene class icap
NP_001255758.1
  • Confirmed by transcript evidence;
    Product from WormBase gene class icap

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13785743..13786961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268828.2 → NP_001255757.1  Integrin Cytoplasmic domain-Associated Protein homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255757.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62480
    Conserved Domains (1) summary
    cl17171
    Location:25 → 136
    PH-like; Pleckstrin homology-like domain

  2. NM_001268829.4 → NP_001255758.1  Integrin Cytoplasmic domain-Associated Protein homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255758.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3NQ97
    Conserved Domains (1) summary
    cl17171
    Location:1 → 77
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
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