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lin-38 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 190028, updated on 2-Nov-2024

Summary

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Official Symbol
lin-38
Official Full Name
C2H2-type domain-containing protein
Primary source
WormBase:WBGene00013006
Locus tag
CELE_Y48E1B.7
See related
AllianceGenome:WB:WBGene00013006
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in negative regulation of vulval development. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lin-38 in Genome Data Viewer
Location:
chromosome: II
Exon count:
9
Sequence:
Chromosome: II; NC_003280.10 (13575925..13585523)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Geranylgeranyl transferase type I subunit beta;Geranylgeranyl transferase type-1 subunit beta Neighboring gene Large ribosomal subunit protein mL37 Neighboring gene Nucleotide-diphospho-sugar transferase domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene C-type lectin domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Ceol CJ, et al. Mol Cell, 2001 Mar. PMID 11463372
  2. The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways. Ferguson EL, et al. Genetics, 1989 Sep. PMID 2806880, Free PMC Article
  3. The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination. Davison EM, et al. Genetics, 2011 Mar. PMID 21196525, Free PMC Article
  4. The histone demethylase UTX enables RB-dependent cell fate control. Wang JK, et al. Genes Dev, 2010 Feb 15. PMID 20123895, Free PMC Article
  5. Caenorhabditis elegans lin-13, a member of the LIN-35 Rb class of genes involved in vulval development, encodes a protein with zinc fingers and an LXCXE motif. Meléndez A, et al. Genetics, 2000 Jul. PMID 10880475, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in negative regulation of vulval development IGI
Inferred from Genetic Interaction
more info
 PubMed 

General protein information

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Preferred Names
C2H2-type domain-containing protein
NP_496852.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13575925..13585523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064451.5 → NP_496852.3  C2H2-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496852.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45950
Nucleotide Protein
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