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spe-38 Uncharacterized protein [ Caenorhabditis elegans ]

Gene ID: 190181, updated on 2-Nov-2024

Summary

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Official Symbol
spe-38
Official Full Name
Uncharacterized protein
Primary source
WormBase:WBGene00013121
Locus tag
CELE_Y52B11A.1
See related
AllianceGenome:WB:WBGene00013121
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in sperm entry. Located in cell cortex. Is expressed in sperm and spermatid. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See spe-38 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003279.8 (10964472..10966382, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene Protein IMPACT homolog Neighboring gene cytochrome-b5 reductase Neighboring gene GTP-binding protein GEM Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The sperm surface localization of the TRP-3/SPE-41 Ca2+ -permeable channel depends on SPE-38 function in Caenorhabditis elegans. Singaravelu G, et al. Dev Biol, 2012 May 15. PMID 22425620, Free PMC Article
  2. A role for sperm in regulation of egg-laying in the nematode C. elegans. McGovern M, et al. BMC Dev Biol, 2007 May 1. PMID 17472754, Free PMC Article
  3. The Caenorhabditis elegans spe-38 gene encodes a novel four-pass integral membrane protein required for sperm function at fertilization. Chatterjee I, et al. Development, 2005 Jun. PMID 15930110
  4. CRISPR/Cas9 Mediated Fluorescent Tagging of Caenorhabditis elegans SPE-38 Reveals a Complete Localization Pattern in Live Spermatozoa. Zuo Y, et al. Biomolecules, 2023 Mar 30. PMID 37189371, Free PMC Article
  5. Spatial Transcriptomics of Nematodes Identifies Sperm Cells as a Source of Genomic Novelty and Rapid Evolution. Rödelsperger C, et al. Mol Biol Evol, 2021 Jan 4. PMID 32785688, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. a novel genetic and physical interaction between two critical sperm function molecules, SPE-38 and TRP-3/SPE-41 in C. elegans was unraveled.
    Title: The sperm surface localization of the TRP-3/SPE-41 Ca2+ -permeable channel depends on SPE-38 function in Caenorhabditis elegans.
  2. SPE-38 was found to concentrate on the pseudopod of mature sperm
    Title: The Caenorhabditis elegans spe-38 gene encodes a novel four-pass integral membrane protein required for sperm function at fertilization.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in single fertilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sperm entry IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Uncharacterized protein
NP_492853.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    10964472..10966382 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060452.9 → NP_492853.2  Uncharacterized protein CELE_Y52B11A.1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492853.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XWF5
Nucleotide Protein
Heading Accession and Version

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