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eyg-1 Homeobox domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 190204, updated on 2-Nov-2024

Summary

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Official Symbol
eyg-1
Official Full Name
Homeobox domain-containing protein
Primary source
WormBase:WBGene00013147
Locus tag
CELE_Y53C12C.1
See related
AllianceGenome:WB:WBGene00013147
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in nervous system development; regulation of transcription by RNA polymerase II; and sensory organ development. Predicted to be located in nucleus. Is expressed in head and pharynx. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See eyg-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (9826448..9827952, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Putative cytochrome P450 CYP13A7 Neighboring gene Putative cytochrome P450 CYP13A8 Neighboring gene Serine/threonine-protein phosphatase Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pax genes in Caenorhabditis elegans: a new twist. Hobert O, et al. Trends Genet, 1999 Jun. PMID 10354580
  2. Unique homeobox codes delineate all the neuron classes of C. elegans. Reilly MB, et al. Nature, 2020 Aug. PMID 32814896, Free PMC Article
  3. A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis. Ma X, et al. Nat Methods, 2021 Aug. PMID 34312566
  4. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  5. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sensory organ development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in intracellular organelle IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Homeobox domain-containing protein
NP_496116.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    9826448..9827952 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063715.2 → NP_496116.1  Homeobox domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496116.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01996
    Conserved Domains (2) summary
    pfam00046
    Location:206 → 259
    Homeobox; Homeobox domain
    cl21459
    Location:48 → 101
    HTH; Helix-turn-helix domains
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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