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Y53G8B.1 maleylacetoacetate isomerase [ Caenorhabditis elegans ]

Gene ID: 190243, updated on 2-Nov-2024

Summary

Official Symbol
Y53G8B.1
Official Full Name
maleylacetoacetate isomerase
Primary source
WormBase:WBGene00021817
Locus tag
CELE_Y53G8B.1
See related
AllianceGenome:WB:WBGene00021817
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glutathione transferase activity and maleylacetoacetate isomerase activity. Predicted to be involved in L-phenylalanine catabolic process and glutathione metabolic process. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Orthologous to human GSTZ1 (glutathione S-transferase zeta 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See Y53G8B.1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (3129277..3131649)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene Magnesium transporter NIPA2 Neighboring gene Detyrosinated tubulin alpha-3 chain Neighboring gene UPF0506 domain-containing protein Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables glutathione transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables maleylacetoacetate isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables maleylacetoacetate isomerase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in L-phenylalanine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in L-phenylalanine catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in aromatic amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tyrosine catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
maleylacetoacetate isomerase
NP_497662.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    3129277..3131649
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065261.5NP_497662.1  maleylacetoacetate isomerase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497662.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N4S0
    Conserved Domains (3) summary
    cd03191
    Location:89207
    GST_C_Zeta; C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases
    TIGR01262
    Location:18211
    maiA; maleylacetoacetate isomerase
    cl00388
    Location:576
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold