U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rom-5 rhomboid protease [ Caenorhabditis elegans ]

Gene ID: 190260, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
rom-5
Official Full Name
rhomboid protease
Primary source
WormBase:WBGene00004404
Locus tag
CELE_Y54E10A.14
See related
AllianceGenome:WB:WBGene00004404
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in signal peptide processing. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See rom-5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (3217288..3222955, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DOMON domain-containing protein Neighboring gene RRM domain-containing protein Neighboring gene CDT1 Geminin-binding domain-containing protein Neighboring gene Thioredoxin-like protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid. Dutt A, et al. PLoS Biol, 2004 Nov. PMID 15455032, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in signal peptide processing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
rhomboid protease
NP_001379293.1
  • Confirmed by transcript evidence
NP_491125.4
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3217288..3222955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001393189.1 → NP_001379293.1  rhomboid protease [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6V7QZA6
    Conserved Domains (1) summary
    cl21536
    Location:169 → 310
    Rhomboid; Rhomboid family

  2. NM_058724.6 → NP_491125.4  rhomboid protease [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491125.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N3E5
    Conserved Domains (1) summary
    cl21536
    Location:161 → 302
    Rhomboid; Rhomboid family
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools