U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

zipt-2.3 Zinc transporter ZIP3 [ Caenorhabditis elegans ]

Gene ID: 190293, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
zipt-2.3
Official Full Name
Zinc transporter ZIP3
Primary source
WormBase:WBGene00013207
Locus tag
CELE_Y54G9A.4
See related
AllianceGenome:WB:WBGene00013207
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Located in gut granule. Is expressed in intestine. Orthologous to human SLC39A1 (solute carrier family 39 member 1) and SLC39A2 (solute carrier family 39 member 2). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See zipt-2.3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (13712906..13715879, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Potassium voltage-gated channel subfamily KQT member 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Serpentine Receptor, class E (Epsilon)

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Lysosome-related organelles contain an expansion compartment that mediates delivery of zinc transporters to promote homeostasis. Mendoza AD, et al. Proc Natl Acad Sci U S A, 2024 Feb 13. PMID 38330011, Free PMC Article
  2. A pathway for low zinc homeostasis that is conserved in animals and acts in parallel to the pathway for high zinc homeostasis. Dietrich N, et al. Nucleic Acids Res, 2017 Nov 16. PMID 28977437, Free PMC Article
  3. A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Chapman EM, et al. Nat Commun, 2019 Apr 17. PMID 30996251, Free PMC Article
  4. The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity. Bailly AP, et al. Cell Rep, 2019 Oct 1. PMID 31577950, Free PMC Article
  5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in metal ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in zinc ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in zinc ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in gut granule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Zinc transporter ZIP3
NP_496876.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13712906..13715879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064475.5 → NP_496876.1  Zinc transporter ZIP3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496876.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XWH3
    Conserved Domains (1) summary
    pfam02535
    Location:5 → 315
    Zip; ZIP Zinc transporter
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools