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Y73B6BL.14 DNA ligase ATP-dependent N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 190650, updated on 2-Nov-2024

Summary

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Official Symbol
Y73B6BL.14
Official Full Name
DNA ligase ATP-dependent N-terminal domain-containing protein
Primary source
WormBase:WBGene00022237
Locus tag
CELE_Y73B6BL.14
See related
AllianceGenome:WB:WBGene00022237
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ATP binding activity; DNA binding activity; and DNA ligase (ATP) activity. Predicted to be involved in DNA recombination and DNA repair. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 20 and pancreatic cancer. Orthologous to human LIG3 (DNA ligase 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y73B6BL.14 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (6342471..6342976, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Macrophage migration inhibitory factor Neighboring gene PNPLA domain-containing protein Neighboring gene RRM domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Biogenesis of lysosome-related organelles complex 1 subunit 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA ligase (ATP) activity IEA
Inferred from Electronic Annotation
more info
  
enables ligase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA ligase ATP-dependent N-terminal domain-containing protein
NP_500970.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    6342471..6342976 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068569.5 → NP_500970.2  DNA ligase ATP-dependent N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500970.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9GUG2
    Conserved Domains (1) summary
    pfam04675
    Location:14 → 88
    DNA_ligase_A_N; DNA ligase N-terminus
Nucleotide Protein
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